The most consistently well-reviewed MK-677 sources in the research community are Chemyo, Swiss Chems, and Science Bio (when in stock). Key things to look for: third-party COA (certificate of analysis) from an independent lab, stated purity above 98%, and transparent batch testing. Avoid any vendor that does not publish COAs.
How long does MK-677 stay in your system?
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MK-677 (ibutamoren) has a half-life of approximately 24 hours, meaning it takes 5–7 days to clear completely from your system. It will not clear standard drug tests as it is not a controlled substance, but specialized sports doping tests can detect it.
Does MK-677 cause water retention?
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Yes — water retention is one of the most commonly reported side effects of MK-677, especially in the first 4–6 weeks. The elevated IGF-1 levels caused by MK-677 increase aldosterone sensitivity, causing the kidneys to retain sodium and water. Most users see this subside after the body adjusts. Reducing sodium intake and staying well-hydrated can help manage this effect.
Does MK-677 suppress natural testosterone?
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MK-677 does not suppress testosterone or the HPG axis (unlike SARMs or anabolic steroids). It works on the GH/IGF-1 axis only. No PCT (post-cycle therapy) is required after an MK-677 cycle. This is one reason it remains popular — it can be used without the hormonal recovery concerns associated with other performance-enhancing compounds.
